Fig. 1.

Antibodies are not required for control of primary MCMV infection and establishment of latency. (Left panel) Kinetics of MCMV clearance after primary infection in B cell deficient and control mice. (Center panels) Twelve weeks after infection, both groups of mice were in latency and showed no differences in load of latent viral genome. (Upper right panel) Latently infected mice were subjected to immunosupression by sub-lethal-γ-irradiation combined with cytolytic antibodies against T cells and NK cells. (Lower right panel) In addition, a group of latently infected and immunodepleted B cell deficient mice received hyperimmune anti-MCMV sera. Adapted from ©1994 JONJIĆ et al. Originally published in JOURNAL OF EXPERIMENTAL MEDICINE. https://doi.org/10.1084/JEM.179.5.1713 [27].