A gap-junction blocker acutely reverts the effects of photoinhibition. A–C, The effects of CBX administration on the local photoinhibition of MNs. A, Representative plots of GCaMP fluorescent intensity in control (left) and upon CBX administration (right) are shown. B, C, Changes in the frequency of motor waves (B) and of baseline fluorescent intensity in A3 contra neuropile (C), upon photoinhibition of MNs in A5, are shown for before and after CBX administration. **p < 0.01, ***p < 0.001 (Wilcoxon signed-rank test; B, C, left, middle); *p < 0.05, ***p < 0.001 (Mann–Whitney U test; B, C, right).