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. 2018 Jan 3;38(1):183–199. doi: 10.1523/JNEUROSCI.1640-17.2017

Figure 7.

Figure 7.

Interaction of PKD1 and N-cadherin promotes the binding of N-cadherin and β-catenin. A, Coimmunoprecipitation of N-cadherin with β-catenin in N2a cells cotransfected N-cadherin with vector, hPKD1, or DN-hPKD1. n = 5. **p < 0.01 (one-way ANOVA with Bonferroni's post hoc). B, C, N-cadherin 836–871aa deletion or Ser869, 871, and 872Ala mutation decreased its binding intensity with β-catenin in N2a cells. B, n = 3. C, n = 4. B. *p < 0.05 (unpaired t test). **p < 0.01 (unpaired t test). C. *p < 0.05 (paired t test). **p < 0.01 (paired t test). Data are mean ± SEM.