Table 2. Clinical condition of patients on candidemia onset, including comparison between subgroups according to the outcome.
| Characteristics of patients, N (%) | All patients (N = 68) |
30-day outcome | P-value* | ||
|---|---|---|---|---|---|
| Survival (N = 30) |
Death (N = 38) |
||||
| Sepsis | 53 (77.9) | 20 (66.7) | 33 (86.8) | 0.046 | |
| Severe Sepsis | 29 (42.6) | 5 (16.7) | 24 (63.2) | <0.001 | |
| Septic Shock | 18 (26.5) | 4 (13.3) | 14 (36.8) | 0.029 | |
| Vital Signs | |||||
| Fever | 29 (44.6) | 16 (53.3) | 13 (37.1) | 0.191 | |
| Heart Rate | Bradycardia | 2 (3.3) | 1 (3.8) | 1 (2.9) | 0.936 |
| Normocardia | 20 (32.8) | 9 (34.6) | 11 (31.4) | ||
| Tachycardia | 39 (63.9) | 16 (61.5) | 23 (65.7) | ||
| Respiratory Frequency | Bradypnea | 0 | 0 | 0 | 0.609 |
| Eupnea | 21 (32.3) | 10 (35.7) | 11 (29.7) | ||
| Tachypnea | 44 (67.7) | 18 (64.3) | 26 (70.3) | ||
| Blood Pressure | Hypotension | 24 (40.0) | 5 (19.2) | 19 (55.9) | 0.006 |
| Normotension | 19 (31.7) | 9 (34.6) | 10 (29.4) | ||
| Hypertension | 17 (28.3) | 12 (46.2) | 5 (14.7) | ||
| Blood Count | |||||
| Blood Leucocyte Count | Leukopenia | 5 (8.5) | 1 (4.2) | 4 (11.4) | 0.224 |
| Normal | 20 (33.9) | 11 (45.8) | 9 (25.7) | ||
| Leukocytosis | 34 (57.6) | 12 (50.0) | 22 (62.9) | ||
| Blood Neutrophil Count | Neutropenia | 3 (5.1) | 0 | 3 (8.6) | 0.042 |
| Normal | 24 (40.7) | 14 (58.3) | 10 (28.6) | ||
| Neutrophilia | 32 (54.2) | 10 (41.7) | 22 (62.9) | ||
| Blood Lymphocyte Count | Lymphopenia | 18 (30.5) | 7 (29.2) | 11 (31.4) | 0.175 |
| Normal | 33 (55.9) | 16 (66.7) | 17 (48.6) | ||
| Lymphocytosis | 8 (13.6) | 1 (4.2) | 7 (20.0) | ||
| Anemia | 55 (91.7) | 23 (92.0) | 32 (91.4) | 0.937 | |
| Blood Platelet Count | Thrombocytopenia | 27 (46.6) | 5 (21.7) | 22 (62.9) | |
| Normal | 28 (48.3) | 17 (73.9) | 11 (31.4) | 0.006 | |
| Thrombocytosis | 3 (5.2) | 1 (4.3) | 2 (5.7) | ||
Candidemia onset was defined as the day of first positive blood culture for Candida species. Some information was missing in patients' records; therefore the valid N varies according to the variable.
* Student t Test/Mann-Whitney Test (continuous data) or Chi-Square Test/Fisher Exact Test (categorical data).