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. 2019 Aug 22;14(8):e0221033. doi: 10.1371/journal.pone.0221033

Table 4. Antifungal stewardship in patients with candidemia, including comparison between subgroups according to the outcome.

Characteristics of patients, N (%) All patients
(N = 68)
30-day outcome P-value*
Survival
(N = 30)
Death
(N = 38)
Previous exposure to antifungals 11 (16.2) 4 (13.3) 7 (18.4) 0.572
Antifungal Treatment 41 (61.2) 20 (69.0) 21 (55.3) 0.254
Timing of antifungal administration** (days; mean ± SD) 5.0 ± 6.0 5.8 ± 7.3 4.2 ± 4.3 0.423
Adequate antifungal dosage 28 (68.3) 13 (65.0) 15 (71.4) 0.658

Previous exposure to antifungals was collected from medical records within the preceding 30 days from the candidemia onset (defined as the day of first positive blood culture for Candida species). Some information was missing in patients' records; therefore the valid N varies according to the variable.

* Student t Test/Mann-Whitney Test (continuous data) or Chi-Square Test/Fisher Exact Test (categorical data).

**Timing of antifungal administration: Interval between candidemia onset and initiation of antifungal treatment.