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. 2018 Mar 7;38(10):2454–2470. doi: 10.1523/JNEUROSCI.2496-17.2018

Table 3.

Effects of remifentanil suspension on mood: Experiment 2a

SC T1
OS T1
SC T2
OS T2
Mean SEM Mean SEM Mean SEM Mean SEM
Session 1
    Drowsy/alert 2.93 0.43 2.53 0.49 5.23 0.51 3.62 0.49
    Excited/calm 2.33 0.41 1.83 0.30 1.33 0.34 1.43 0.39
    Feeble/strong 2.85 0.47 2.28 0.35 3.77 0.55 2.72 0.51
    Clear-headed/muzzy 8.22 0.47 8.48 0.47 6.00 0.69 7.10 0.67
    Clumsy/well-coordinated 2.87 0.43 2.58 0.40 4.33 0.57 3.60 0.51
    Energetic/lethargic 6.52 0.51 6.90 0.40 4.92 0.55 9.45 3.28
    Discontented/contended 2.50 0.59 1.55 0.22 1.97 0.38 1.82 0.36
    Tranquil/troubled 7.97 0.52 7.48 0.64 7.92 0.40 8.00 0.37
    Quick-witted/mentally slow 7.78 0.52 8.42 0.48 6.67 0.55 7.27 0.73
    Relaxed/tense 7.23 0.48 8.03 0.38 7.53 0.57 8.47 0.36
    Dreamy/attentive 3.17 0.60 2.33 0.55 4.23 0.59 3.70 0.71
    Proficient/incompetent 7.90 0.50 8.45 0.43 6.88 0.62 8.22 0.31
    Sad/happy 2.45 0.54 1.57 0.31 3.35 0.78 1.77 0.44
    Amicable/antagonistic 8.45 0.35 9.00 0.27 7.73 0.46 8.82 0.32
    Bored/interested 2.27 0.36 1.77 0.41 3.00 0.68 1.85 0.47
    Gregarious/withdrawn 5.78 0.53 5.72 0.29 5.33 0.55 5.38 0.43
    Insecure/secure 2.48 0.55 1.95 0.34 2.28 0.51 1.80 0.40
SC T3
OS T3
SC T4
OS T4
Mean SEM Mean SEM Mean SEM Mean SEM
Session 2
    Drowsy/alert 3.20 0.53 2.92 0.40 4.53 0.54 3.72 0.57
    Excited/calm 1.65 0.28 1.38 0.32 2.18 0.44 1.22 0.24
    Feeble/strong 2.90 0.50 3.45 0.78 3.68 0.46 3.32 0.53
    Clear-headed/muzzy 7.35 0.60 8.17 0.54 6.00 0.65 7.82 0.43
    Clumsy/well-coordinated 3.02 0.45 2.62 0.61 4.73 0.50 3.63 0.43
    Energetic/lethargic 6.38 0.56 6.85 0.58 5.38 0.55 6.32 0.50
    Discontented/contended 1.65 0.48 1.98 0.62 1.83 0.40 1.70 0.56
    Tranquil/troubled 7.45 0.59 8.35 0.31 7.85 0.32 8.40 0.32
    Quick-witted/mentally slow 8.10 0.37 8.58 0.39 7.50 0.57 7.50 0.59
    Relaxed/tense 7.73 0.57 8.48 0.35 7.33 0.62 8.25 0.37
    Dreamy/attentive 2.65 0.36 1.88 0.39 3.78 0.65 2.58 0.51
    Proficient/incompetent 7.60 0.46 8.68 0.35 7.17 0.55 8.35 0.36
    Sad/happy 2.05 0.51 1.17 0.22 2.82 0.58 1.58 0.33
    Amicable/antagonistic 8.15 0.47 8.87 0.29 7.55 0.63 9.02 0.29
    Bored/interested 2.85 0.63 1.60 0.32 3.62 0.73 1.93 0.46
    Gregarious/withdrawn 5.55 0.58 5.90 0.44 5.58 0.43 5.65 0.39
    Insecure/secure 1.98 0.46 1.42 0.24 2.42 0.50 1.30 0.28

aBefore and after each experimental session, subjects had to rate their current mood on a 17 item questionnaire. Each item consisted of a VAS with opposing verbal descriptors at each end. Ratings were scored from 0 to 10. Data are the average group scores (mean ± SEM). SC, Saline control group; OS, opioid suspension group; T1, before Session 1; T2, after Session 1; T3, before Session 2; T4, after Session 2.