Figure 3.

ACC-DMS disconnection has no influence on acute nociceptive sensation of mice. A, Mice with ACC-DMS disconnection exhibited normal mechanical pain response in von Frey test. Left, t₍₁₈₎ = 0. Right, t₍₁₈₎ = 0; p > 0.9999. The bilateral hindpaws were examined. B, Mice with ACC-DMS disconnection displayed comparable heat pain response in the radiant heat test. t₍₁₄₎ = 0.6884, p = 0.5024. C, No significant difference of capsaicin-induced chemical pain was observed in mice with ACC-DMS disconnection. Capsaicin (10 μg/10 μl) was intradermally injected into the right side of the cheek. t₍₁₄₎ = 0.4438, p = 0.6640. All data are shown as mean ± SEM. p > 0.05 compared with vehicle groups, Student's t test. n = 8–10 mice for each group.