Table 1.
Control | Saporin | Reduction, % | p | |
---|---|---|---|---|
ChAT | ||||
NBM | 355.89 ± 9.45 | 161.60 ± 6.19 | 54.6 | <0.001* |
MS/VDB | 394.33 ± 8.59 | 379.10 ± 9.01 | 3.9 | 0.134 |
HDB | 128.56 ± 6.09 | 127.60 ± 5.80 | 0.7 | 0.884 |
Parvalbumin | ||||
NBM | 242.33 ± 9.45 | 223.10 ± 6.82 | 7.9 | 0.112 |
Summary of the findings following the ChAT and parvalbumin immunostaining shows that there was a significant loss of cells in the NBM of ACh-NBM-lesioned rats compared to sham-lesioned rats. There were no group differences in the number of ChAT-immunoreactive cells in the MS/VDB and in the HDB, and no differences in the number of parvalbumin-immunoreactive cells in the NBM.
*Indicates significant difference at p < 0.05.