Table 2.
Control | Saporin | Reduction, % | p | |
---|---|---|---|---|
Fr3 (+2.76) | 0.70 ± 0.01 | 0.48 ± 0.01 | 30.6 | <0.001* |
Prelimbic cortex (+2.76) | 0.70 ± 0.01 | 0.46 ± 0.01 | 33.9 | <0.001* |
Motor/sensory (+1.32) | 0.65 ± 0.01 | 0.44 ± 0.01 | 32.0 | <0.001* |
Piriform (+0.60) | 0.48 ± 0.01 | 0.46 ± 0.01 | 2.9 | 0.207 |
Hippocampus (3.24) | 0.59 ± 0.01 | 0.59 ± 0.01 | −0.1 | 0.971 |
Parietal (−3.96) | 0.61 ± 0.01 | 0.43 ± 0.01 | 29.1 | <0.001* |
Visual (−4.80 to −5.16) | 0.53 ± 0.01 | 0.44 ± 0.01 | 17.9 | <0.001* |
The effect of 192 IgG-saporin lesion on the adjusted OD values measured from various cortical regions following AChE staining, together with the results of statistical analysis. Anterior–posterior distance from bregma at which OD value was measured is shown in brackets.
*Indicates significant difference at p < 0.05.