Skip to main content
. 2018 Apr 18;38(16):3988–4005. doi: 10.1523/JNEUROSCI.2350-17.2018

Table 3.

Behavioral measures (mean + SEM) of the visual 5-CSRTT following the cholinergic NBM lesion

Behavioral measure TD = 1 s TD = 0.5 s TD = 0.25 s Variable ITI
Correct response, %
    Control 77.78 ± 1.98 64.07 ± 3.50 49.07 ± 4.15 62.96 ± 3.57
    Saporin 77.17 ± 3.63 49.83 ± 3.10* 31.50 ± 3.20* 65.83 ± 3.84
Incorrect response, %
    Control 6.30 ± 0.91 12.22 ± 2.20 22.59 ± 2.77 8.33 ± 1.69
    Saporin 7.17 ± 1.41 18.50 ± 1.83* 18.67 ± 1.81 10.33 ± 2.80
Omission, %
    Control 5.37 ± 1.17 14.63 ± 2.00 19.63 ± 4.02 13.52 ± 1.65
    Saporin 7.17 ± 1.72 25.00 ± 3.51* 32.33 ± 4.31* 11.50 ± 1.48
Premature response, %
    Control 10.56 ± 2.17 9.07 ± 1.69 8.52 ± 1.26 15.00 ± 2.94
    Saporin 8.00 ± 4.08 6.50 ± 1.39 17.33 ± 3.84 12.33 ± 1.80
Correct latency, s
    Control 0.97 ± 0.08 0.76 ± 0.02 0.75 ± 0.03 0.94 ± 0.07
    Saporin 0.88 ± 0.05 0.78 ± 0.03 0.90 ± 0.05 0.95 ± 0.05
Reward latency, s
    Control 1.58 ± 0.15 1.45 ± 0.04 1.42 ± 0.05 1.44 ± 0.06
    Saporin 1.51 ± 0.07 2.11 ± 0.59 1.44 ± 0.05 1.48 ± 0.07
Accuracy, %
    Control 92.76 ± 1.37 83.76 ± 3.43 68.18 ± 2.77 88.35 ± 3.26
    Saporin 91.46 ± 1.37 72.72 ± 3.18* 62.37 ± 3.52 86.24 ± 3.08

Summary of the rats' performance on a visual version of the 5-CSRTT across different testing conditions, following the cholinergic NBM lesion. Note the significant group differences in the percentage of correct responses and percentage of omissions per session under the conditions of increased attentional demand.

*Reflects group difference at p < 0.05.