Skip to main content
. 2018 Apr 18;38(16):3988–4005. doi: 10.1523/JNEUROSCI.2350-17.2018

Table 4.

Behavioral measures (mean + SEM) of the olfactory 5-CSRTT following the cholinergic NBM lesion

Behavioral measure TD = 1 s TD = 0.5 s TD = 0.25 s Variable ITI
Correct response, %
    Control 73.33 ± 2.08 65.37 ± 4.65 51.11 ± 3.07 60.74 ± 3.45
    Saporin 70.33 ± 2.22 47.83 ± 3.64* 33.17 ± 3.58* 66.00 ± 3.23
Incorrect response, %
    Control 10.74 ± 2.08 8.89 ± 1.47 13.33 ± 1.57 11.30 ± 1.96
    Saporin 9.33 ± 1.74 10.00 ± 1.96 19.17 ± 1.15* 9.67 ± 1.77
Omission, %
    Control 7.59 ± 2.68 13.33 ± 4.38 23.52 ± 2.58 12.04 ± 2.45
    Saporin 8.67 ± 1.57 31.00 ± 5.24* 34.83 ± 3.20* 9.17 ± 1.71
Premature response, %
    Control 8.33 ± 1.39 12.41 ± 2.39 11.85 ± 1.85 15.74 ± 2.08
    Saporin 11.67 ± 1.69 11.17 ± 2.68 12.50 ± 2.48 14.83 ± 3.02
Correct latency, s
    Control 1.05 ± 0.04 0.98 ± 0.07 0.75 ± 0.05 1.20 ± 0.08
    Saporin 1.04 ± 0.06 0.86 ± 0.07 0.89 ± 0.06 1.12 ± 0.07
Reward latency, s
    Control 1.40 ± 0.04 1.44 ± 0.05 1.36 ± 0.05 1.47 ± 0.07
    Saporin 1.49 ± 0.06 1.47 ± 0.05 1.35 ± 0.05 1.44 ± 0.07
Accuracy, %
    Control 87.56 ± 2.25 87.63 ± 2.29 79.27 ± 3.59 84.05 ± 1.99
    Saporin 88.27 ± 2.20 82.81 ± 2.99 62.31 ± 3.67* 87.27 ± 2.95

Summary of the rats' performance on an olfactory version of the 5-CSRTT across different testing conditions, following the cholinergic NBM lesion. Note the significant group differences in the percentage of correct responses and percentage of omissions per session under the conditions of increased attentional demand.

*Reflects group difference at p < 0.05.