Table 4.
Cluster | Anatomical region | Extent (voxels) | x | y | z | Peak F | Peak Z |
---|---|---|---|---|---|---|---|
1 | Left mid frontal gyrus (BA8) | 7 | −24 | 17 | 64 | 13.44 | 5.45 |
2 | Left mid frontal gyrus (BA46) | 4 | −33 | 56 | 19 | 11.24 | 4.98 |
3 | Left BA6, BA44, BA45 | 171 | −51 | 26 | 25 | 17.64 | 6.20 |
Left mid frontal gyrus (BA44) | 69 | −39 | 11 | 34 | |||
Left precentral gyrus (BA6) | 14 | −36 | 2 | 61 | |||
Left inferior frontal gyrus (BA45) | 88 | −51 | 26 | 25 | |||
4 | Left inferior frontal gyrus (BA45) | 17 | −48 | 44 | 7 | 14.14 | 5.59 |
5 | Left supplementary motor area (BA32) | 8 | −6 | 20 | 46 | 12.07 | 5.16 |
6 | Left posterior cingulum | 24 | −3 | −34 | 31 | 15.01 | 5.75 |
7 | Left inferior parietal lobe (BA40) | 170 | −36 | −58 | 40 | 16.60 | 6.30 |
8 | Left angular gyrus | 19 | −57 | −46 | 28 | 12.81 | 5.32 |
9 | Left precuneus (BA7) | 19 | −9 | −67 | 43 | 14.99 | 5.75 |
10 | Left mid temporal gyrus (BA21) posterior | 28 | −63 | −43 | −5 | 17.85 | 6.23 |
11 | Left mid temporal gyrus (BA21) anterior | 70 | −60 | −13 | −11 | 14.71 | 5.70 |
12 | Right mid temporal gyrus (BA21) anterior | 194 | 51 | −25 | −8 | 26.27 | 7.34 |
13 | Left/right caudate/thalamus | 245 | 0 | −10 | 10 | 16.51 | 6.02 |
Left caudate | 62 | −18 | 5 | 19 | |||
Left thalamus | 64 | −3 | −10 | 10 | |||
Right caudate | 38 | 18 | 5 | 16 | |||
Right thalamus | 52 | 3 | −7 | 7 | |||
14 | Left cerebellum (crus I/II) | 118 | −36 | −61 | −32 | 17.85 | 6.23 |
15 | Right cerebellum (crus I/II) | 224 | 15 | −79 | −35 | 20.23 | 6.59 |
16 | Left brainstem | 11 | −3 | −28 | −14 | 13.77 | 5.52 |
17 | Right brainstem | 7 | 15 | −25 | −11 | 12.23 | 5.20 |
aWhole-brain analysis revealed significant activation during drug imagery (relative to baseline imagery), for at least one of the four drug-setting conditions, in the clusters listed (PFWE < 0.05 at the voxel level). Post hoc analyses indicated significant drug × setting × time interaction in the regions in bold.