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. 2018 May 30;38(22):5182–5195. doi: 10.1523/JNEUROSCI.0019-18.2018

Table 4.

Brain activation during drug imagerya

Cluster Anatomical region Extent (voxels) x y z Peak F Peak Z
1 Left mid frontal gyrus (BA8) 7 −24 17 64 13.44 5.45
2 Left mid frontal gyrus (BA46) 4 −33 56 19 11.24 4.98
3 Left BA6, BA44, BA45 171 −51 26 25 17.64 6.20
Left mid frontal gyrus (BA44) 69 −39 11 34
Left precentral gyrus (BA6) 14 −36 2 61
Left inferior frontal gyrus (BA45) 88 −51 26 25
4 Left inferior frontal gyrus (BA45) 17 −48 44 7 14.14 5.59
5 Left supplementary motor area (BA32) 8 −6 20 46 12.07 5.16
6 Left posterior cingulum 24 −3 −34 31 15.01 5.75
7 Left inferior parietal lobe (BA40) 170 −36 −58 40 16.60 6.30
8 Left angular gyrus 19 −57 −46 28 12.81 5.32
9 Left precuneus (BA7) 19 −9 −67 43 14.99 5.75
10 Left mid temporal gyrus (BA21) posterior 28 −63 −43 −5 17.85 6.23
11 Left mid temporal gyrus (BA21) anterior 70 −60 −13 −11 14.71 5.70
12 Right mid temporal gyrus (BA21) anterior 194 51 −25 −8 26.27 7.34
13 Left/right caudate/thalamus 245 0 −10 10 16.51 6.02
Left caudate 62 −18 5 19
Left thalamus 64 −3 −10 10
Right caudate 38 18 5 16
Right thalamus 52 3 −7 7
14 Left cerebellum (crus I/II) 118 −36 −61 −32 17.85 6.23
15 Right cerebellum (crus I/II) 224 15 −79 −35 20.23 6.59
16 Left brainstem 11 −3 −28 −14 13.77 5.52
17 Right brainstem 7 15 −25 −11 12.23 5.20

aWhole-brain analysis revealed significant activation during drug imagery (relative to baseline imagery), for at least one of the four drug-setting conditions, in the clusters listed (PFWE < 0.05 at the voxel level). Post hoc analyses indicated significant drug × setting × time interaction in the regions in bold.