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. 2018 May 30;38(22):5153–5167. doi: 10.1523/JNEUROSCI.3270-17.2018

Figure 2.

Figure 2.

GrC stimulation can evoke a wide range of PC spike gains. A, Spike gain distribution in PCs (n = 51) in response to 1 (blue), 3 (red), or 7 (green) GrC stimulations at 200 Hz. ***p ≤ 0.001 Wilcoxon rank test. B, Pauses and decreases in firing rate in PC discharge are mediated by FFI. Left, Example of a PC showing a negative spike gain in response to 1, 3, or 7 stimulations of GrCs in control condition (black traces) and a positive spike gain in picrotoxin condition (100 μm; gray thick traces). Right, Averaged effect of picrotoxin application on spike gain (n = 7). Error bars indicate SEM.