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The effect of systemic naproxen on CSD-induced changes in CBF. A, Changes in CBF following induction of CSD in vehicle- and naproxen-treated animals. B, CBF changes during the hyperemia stage, showing the enhancing effect of naproxen. C, CBF changes during the hypoperfusion phase, 10–60 min following CSD, depicting the inhibitory effect of naproxen. p Values are based on a Mann–Whitney U test. PP, Pinprick.
