Figure 9.
Blockade of 5-HT2A and 5-HT7 receptors does not affect RSP-induced locomotor-like activity. A, Schematic of experimental procedure. B, Integrated activities of lumbar ventral roots during an episode of fictive locomotion evoked by the RSP. C, Circular plots from the same recording showing phase alternation between both bilateral L2 (top) and ipsilateral L5 and L2 (bottom) activities. D–F, Episode of RSP-induced fictive locomotion (with corresponding polar plots) in the same preparation in the presence of serotonergic 5-HT2A (ketanserin, 10 μm) and 5-HT7 (SB269970, 10 μm) receptor antagonists.