Figure 2.

Local generation of OPCs in the dorsal forebrain of PDGFRα mutants. A–F, P0 forebrain tissues from control and PDGFRα cko mice were examined for PDGFRα, Olig1, and Sox10 by RNA ISH. G, H, Statistical analyses of various OPCs in the dorsal and ventral forebrain. While Olig1 expression in the mutants was mostly detected in the SVZ surrounding the lateral ventricle, expression of Sox10 was nearly undetectable at this stage. White dot line indicates the boundary of dorsal and ventral forebrain.