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Dorsal distribution of OPCs in P4 PDGFRα mutant brain. A–F, P4 forebrain tissues from control and PDGFRα cko mice were examined for expression of OPC markers. G, H, Statistical analyses of various OPCs in the dorsal and ventral forebrain. At this stage, Olig1+ and Sox10+ cells in the mutants were mostly confined to the dorsal cortex adjacent to the lateral ventricle. White dot line indicates the boundary of dorsal and ventral forebrain.
