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. Author manuscript; available in PMC: 2019 Aug 22.
Published in final edited form as: Cell. 2018 Apr 19;173(3):542–544. doi: 10.1016/j.cell.2018.04.001

Fig. 1.

Fig. 1

(A) Shear stress arising from fluid flow across a surface parallel to the direction of flow. (B) GPR68 detects flow-mediated shear stress, which activates Gαq/11 signaling and increases intracellular Ca2+ levels.