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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Mutat Res. 2019 Feb 10;781:186–206. doi: 10.1016/j.mrrev.2019.02.001

Table 4:

Description and weight of studies selected for the current meta-analyses.

Study (Author, Year) Case No. (Exp/Tot) Exposure Category Risk Estimatea (95% CI) Weightb
AHS 2018 AHS 2005
AHS Cohort

Andreotti et al. [24] 55/575 ≥2610 d/I c,d 1.12 (0.83, 1.51)e 54.04 --
De Roos (2005) [19] 22/92 ≥337.2 d/Ic 0.8 (0.5, 1.4)f -- 28.43

Case-Control

De Roos (2003) [15] 36/650 Ever, log 2.10 (1.10, 4.00) 11.61 18.08
Eriksson et al. [16] 17/910 >10 d/y 2.36 (1.04, 5.37) 7.18 11.18
Hardell et al. [17] 8/515 Ever 1.85 (0.55, 6.20) 3.30 5.14
McDuffie et al. [42] 23/517 >2 d/y 2.12 (1.2, 3.73) 15.05 23.43
Orsi et al. [18] 12/244 Ever 1.0 (0.5, 2.2) 8.82 13.73

Abbreviations: AHS, Agricultural Health Study; d, days; exp, exposed; I, lifetime; log, logistic regression; tot, total; y, year.

a

Relative risk (RR) reported in both AHS analyses and odds ratio (OR) reported in all case-control studies.

b

Weight given to each study in the fixed effects model.

c

Intensity-weighted lifetime exposure days (cumulative exposure days multiplied by intensity score)

d

20 years or more lag (time between study recruitment and NHL onset).

e

Reference group is unexposed

f

Reference group is lowest exposed