Figure 6.
Registration of imaging with gross observation of red blood cell phantom liquefaction. (a) Gross observation of liquefaction generated by histotripsy in a red blood cell phantom with the liquefaction zone outlined in green, (b) coregistration of passive cavitation imaging (PCI) acoustic power and red blood cell liquefaction, (c) coregistration of plane wave grayscale and red blood cell liquefaction, (d) parametric T2 map of red blood cell liquefaction, (e) coregistration of PCI acoustic power and T2 map, and (f) coregistration of plane wave grayscale and T2 map. The liquefaction zone outline is shown in panels (a)-(c). The histotripsy pulse (1 MHz fundamental frequency, 5 μs pulse duration, 17 MPa peak negative pressure) propagated from left to right in the image. The azimuth/range dimensions of the diagnostic ultrasound imaging plane are indicated in the panel (a).