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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Curr Opin Struct Biol. 2019 Feb 22;59:19–28. doi: 10.1016/j.sbi.2019.01.006

Figure 2. The PPD and CPD branches of heme b biosynthesis carry out similar chemical transformations in different orders.

Figure 2.

Although some of the enzymes between the branches are homologous, a change in the order in which each is used creates different porphyrin intermediates. The terminal enzyme of the CPD pathway (ChdC) is completely unique. As knowledge about these pathways has evolved, new nomenclature for the enzymes that catalyze each individual step has been developed. For clarity, the most recently proposed nomenclature is used here3.