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Tolerogenic activity of HEL-oligomers (DSS). Two groups of five BALB/c mice were pre-exposed with saline or HEL-oligomers (DSS) and challenged with native HEL as in Fig. 3. Serum anti-HEL IgG levels in mice pretreated with HEL oligomers (DSS) (○) or with saline (□). P-values were calculated using Student's t-test. Statistical significance was set at P < 0.05.
