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. 2019 Jul 6;411(23):5951–5962. doi: 10.1007/s00216-019-01998-6

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — nES GEMMA yields a peak for HPV16-based VLPs allowing its subsequent M_W determination based on the correlation presented in Fig. 3. The calculated M_W (19,975 kDa) is in good accordance with the theoretically expected M_W value (20,260 kDa, based on VLP stoichiometry and database M_W values for individual viral proteins)