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. 2019 Aug 22;9:203. doi: 10.1038/s41398-019-0534-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Pairwise comparison CHR-PLB>HC with clusters in bilateral frontal operculae and left insula/parietal operculum. b Pairwise comparison CHR-PLB>CHR-CBD with cluster in left insula/claustrum. c Three-way ANOVA CHR-PLB>CHR-CBD>HC with clusters in left frontal operculum and left insula/parietal operculum. d Mean b-value parameter estimates extracted from the two clusters generated by ANOVA for each group (CHR-PLB, CHR-CBD, and HC) showing increased activation in CHR-PLB relative to HC with CHR-CBD intermediate in the left frontal operculum and left insula/parietal operculum. e Negative correlation between mean b-value from ANOVA-derived cluster of left insula/parietal operculum and mean reaction time for salience condition in HC. f Positive correlation between mean b-value from ANOVA-derived cluster of left insula/parietal operculum and CAARMS positive subscale in CHR-PLB. g Negative correlation between mean b-value from ANOVA-derived cluster of left insula/parietal operculum and difference in mean reaction time between neutral and salience condition in CHR-PLB