Figure 3.

Top canonical pathways assigned by the ingenuity pathway analysis for the 17 differentially expressed proteins expressed in individuals with and without TC. The canonical pathway of LXR/RXR activation is presented. Each line and arrow indicates a known functional or physical interaction. Green colored shapes indicate the downregulated expression of a pathway-associated protein. Solid lines indicate direct interactions and dashed lines indicate indirect interactions. LXR/RXR, liver X receptor/retinoid X receptor.