Table 2.
Hypothesis test results of covariates affecting on vancomycin clearance (CL)
| Hypothesis test | OBJ | ΔOBJ | P-value | Comments |
|---|---|---|---|---|
| Basic model | 2206.3 | |||
| If Gender affect CL ? | 2205.0 | -1.3 | >0.05 | NO |
| If Age affect CL ? | 2097.6 | -108.7 | <0.01 | YES |
| If Weight affect CL ? | 2094.0 | -112.3 | <0.01 | YES |
| If Body surface area affect CL ? | 2095.4 | -110.9 | <0.01 | YES |
| If ALT affect CL ? | 2204.8 | -1.5 | >0.05 | NO |
| If AST affect CL ? | 2204.8 | -1.5 | >0.05 | NO |
| If CRE affect CL ? | 2197.5 | -8.8 | <0.01 | YES |
| If BUN affect CL ? | 2205.6 | -0.7 | >0.05 | NO |
| If GFR affect CL ? | 2140.6 | -65.7 | <0.01 | YES |