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. 2019 Aug 13;70(Suppl 1):S43–S62. doi: 10.3233/JAD-180511

Table 6.

Annotated ontology of molecular function, cellular component, and biological process of significantly detected proteins

Annotated object (GO ID) Fold Enrichment p
Molecular Function
Peptidase Inhibitor Activity (GO:0030414) ≥100 0.008
Lipase Activity (GO:0016298) 39.72 0.025
Peroxidase Activity (GO:0004601) 35.31 0.028
Deacetylase Activity (GO:0019213) 30.75 0.032
Serine-Type Endopeptidase Inhibitor Activity (GO:0004867) 23.25 0.029
Transferase Activity, Transferring Acyl Group (GO:0016746) 22.97 0.034
Metallopeptidase Activity (GO:0008237) 19.59 0.047
Serine-type peptidase activity (GO:0008236) 19.45 0.048
Cellular Component
Macromolecular complex (GO:0032991) ≥100 0.007
Neuronal cell body (GO:0043025) 68.09 0.015
Synapse (GO:0045202) 24.44 0.040
Extracellular space (GO:0005615) 12.59 8.04e–7
Extracellular region (GO:0005576) 6.31 0.040
Biological Process
Regulation of biological process (GO:0003008) 38.13 0.026
Cholesterol metabolic process (GO:0008203) 35.75 8.10e–5
Fatty acid biosynthetic process (GO:0006633) 29.79 0.033
Response to toxic substance (GO:0009636) 25.09 0.039
Defense response to bacterium (GO:0042742) 13.92 0.009
Protein metabolic process (GO:0019538) 12.07 0.002
Phospholipid metabolic process (GO:0006644) 9.39 0.019
Response to external stimulus (GO:0009605) 8.67 0.022
Proteolysis (GO:0006508) 6.38 0.003
Regulation of biological process (GO:0050789) 2.95 0.024