| Patient education |
Strong recommendation |
| Exercise |
Strong recommendation |
| Physical therapy modalities |
|
| Electro-therapeutic applications |
Weak recommendation (As a part of the treatment program) |
| Massage |
Insufficient scientific evidence |
| Cognitive behavioral treatment |
Weak recommendation (As a part of the treatment program) |
| Pharmacotherapy |
Moderate recommendation (Pregabalin) |
| Antiepileptics |
Moderate recommendation (Gabapentin - Benefit-risk calculation should be made) |
| Monoamine oxidase inhibitors (MAOIs) |
Strong recommendation (Not recommended) |
| Nonsteroidal anti-inflammatory drugs (NSAIDs) |
Weak recommendation (Not recommended) |
| Selective serotonin reuptake inhibitors (SSRIs) |
Weak recommendation (Can be used in the treatment of depression and anxiety disorders in patients with FM) |
| Serotonin-noradrenaline reuptake inhibitors (SNRIs) |
Moderate recommendation (Duloxetin, milnacipram) |
| Cyclobenzaprine |
Weak recommendation (Not recommended) |
| Tramadol |
Weak recommendation (Can be used for a short period and with a dose up to 150 mg/day) |
| Tricyclic antidepressants |
Weak recommendation (Amitriptyline can be used at a dose of 10-25 mg/day in patients with fibromyalgia (FM) below 60 years of age, who do not have any cardiac problems and who do not use other antidepressant drugs) |
| Capsaicin |
Weak recommendation (As a part of the treatment program) |
| Drug combinations |
Weak recommendation (Can be used in FM patients, who do not respond to monotherapy under careful observation) |
| Complementary Therapies |
|
| Acupuncture |
Weak recommendation (As a part of the treatment program) |
| Mind-body treatments |
|
| Mindfulness |
Weak recommendation (As a part of the treatment program) |
| Meditative movements |
Weak recommendation (As a part of the treatment program) |
| New treatment approaches |
Strong recommendation (Not recommended) |
| Nutritional supplements and complementary medicine products |
Strong recommendation (Not recommended) |
| Other complementary treatments |
Strong recommendation (Not recommended) |
| Multidisciplinary and Interdisciplinary Treatments |
Strong recommendation |
