TNP-470-induced Zebrafish Embryo Dysmorphology (Representative photomicrographs). Photomicrographs of representative zebrafish embryos following five days of culture in the absence or presence of increasing concentrations of TNP-470. Magnification = 100×. Untreated control (A), TNP-470 (7B, 0.1 μM; 7C, 10 μM; 7D, 1 μM). TNP-470 was teratogenic causing primarily caudal defects and abnormal somite patterning. The asterisks in 7 B shows tail fin abnormalities; in 7C shows tail fin abnormalities, disorganized somites, and forebrain blisters; in 7D shows blisters.