Table 6.

Top ten categories of GO-molecular functions associated with clinically relevant and known genes for schizophrenia.

GeneAnalytics score	GO-molecular functions	Total number of genes identified in GO- molecular functions from integrated databases	Number of matched genes from schizophrenia master list (%)
70.37	Ion channel activity	121	34 (5.5)
61.21	Extracellular ligand-gated ion channel activity	47	22 (3.6)
54.38	Ionotropic glutamate receptor activity	18	15 (2.4)
54.38	Extracellular-glutamate-gated Ion channel activity	18	15 (2.4)
39.34	GABA-A receptor activity	19	12 (1.9)
35.31	Ras guanyl-nucleotide exchange factor activity	116	22 (3.6)
35.24	Enzyme binding	364	39 (6.4)
32.98	G-protein coupled serotonin receptor activity	28	12 (1.9)
32.23	Protein heterodimerization activity	482	44 (7.2)
31.58	Drug binding	75	17 (2.7)