Table 3.
Covariance analysis of efficacy between the Two Groups
| Psychometric scores | RIC Group(n = 18) | Control Group(n = 19) | p |
|---|---|---|---|
| HVLT-R | |||
| HVLT1 | 17.02 ± 1.05 | 15.93 ± 1.02 | 0.464 |
| HVLT2 | 4.68 ± 0.73 | 4.56 ± 0.71 | 0.908 |
| HVLT3 | 8.78 ± 0.50 | 7.47 ± 0.48 | 0.069 |
| COWAT | 6.35 ± 0.62 | 5.57 ± 0.60 | 0.372 |
| TMT-A | 105.12 ± 13.09 | 125.70 ± 13.47 | 0.282 |
| TMT-B | 201.64 ± 17.29 | 204.80 ± 17.29 | 0.898 |
| SDMT | 22.82 ± 1.68 | 20.07 ± 1.68 | 0.259 |
| JLO | 23.10 ± 1.23 | 18.56 ± 1.23 | 0.013 |
| Hs-CRP | 2.63 ± 0.74 | 1.19 ± 0.83 | 0.220 |
| IL-6 | 15.85 ± 6.70 | 15.81 ± 4.27 | 0.790 |
| TNF-α | 5.57 ± 1.02 | 5.46 ± 0.72 | 0.679 |
| WMLV (cm3) | 74.21 ± 4.24 | 65.18 ± 3.79 | 0.166 |
| WBWM | |||
| FA | 0.291 ± 0.009 | 0.306 ± 0.009 | 0.336 |
| MD(×10−4) | 9.5 ± 0.32 | 9.0 ± 0.71 | 0.658 |
| NAWM | |||
| FA | 0.292 ± 0.01 | 0.307 ± 0.01 | 0.358 |
| MD(×10−4) | 9.3 ± 0.46 | 8.9 ± 0.62 | 0.485 |
Abbreviations: COWAT Controlled Oral Word Association Test, the outcome was the sum of correct words in the both parts, FA fractional anisotropy, hs-CRP high-sensitive C-reactive protein, HVLT1 immediate memory of Hopkins Verbal Learning Test-Revised (HVLT-R), HVLT2 delayed memory of HVLT-R, HVLT3 recognition test of HVLT-R, IL-6 interleukin 6, JLO Judgment of Line Orientation, MD mean diffusivity, NAWM normal-appearing white matter, SDMT Symbol Digit Modalities Test, TMT-A Trail Making Test A, TMT-B Trail Making Test B, TNF-α tumor necrosis factor-alpha, WBWM whole-brain white matter, WMLV white matter lesion volume