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. 2019 Aug 22;20:437. doi: 10.1186/s12859-019-3028-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Results of differential expression analysis on CMAP dataset. a, percentage of drugs having signature size greater than or equal to 10 for each gene expression analysis method plotted against FDR cutoff. b, average signature size resulted from each gene expression analysis method plotted against FDR cutoff; y-axis was transformed to log-10 scale