Pedigree, mutational analysis, clinical image, and panoramic radiograph. (A) Pedigree of family 2. (B) DNA sequencing chromatogram of normal control. (C) DNA sequencing chromatogram of the proband of family 2. Mutated nucleotide (g.3151C>T, c.2029C>T, p.Q677X) is indicated by red arrow. (D) Frontal photograph of the proband of the family 2 taken at age 8 yrs. (E) Dental panoramic radiograph of the proband of the family 2 taken at age 8 yrs.