. 2019 Aug 21;2(8):e199826. doi: 10.1001/jamanetworkopen.2019.9826

Table 4. General Linear Regression Analyses of the Association of Plasma Amylin Concentration With Brain Volume^a.

Plasma Amylin Concentration	Temporal Lobe Brain Gray Matter Volume, %^b		Logarithm of White Matter Hyperintensities, %^b
Plasma Amylin Concentration	β Estimate (SE)	P Value^c	β Estimate (SE)	P Value^c
High^d	0.17 (0.05)	<.001	−1.85 (0.70)	.008
Extremely high^e	0.02 (0.07)	.82	0.63 (1.09)	.57

^{^a}

The models were adjusted for age, sex, education, smoking, body mass index, diabetes, cardiovascular diseases, APOE4, and high-density lipoprotein. Low plasma amylin concentration (<75 pmol/L) was used as the reference.

^{^b}

Given as a percentage of total cerebral brain volume.

^{^c}

P values adjusted using conventional Bonferroni correction (P < .004).

^{^d}

75 pmol/L to less than 2800 pmol/L.

^{^e}

2800 pmol/L or greater.

Table 4. General Linear Regression Analyses of the Association of Plasma Amylin Concentration With Brain Volumea.

Table 4. General Linear Regression Analyses of the Association of Plasma Amylin Concentration With Brain Volume^a.