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. 2019 Aug 16;10:1960. doi: 10.3389/fimmu.2019.01960

Figure 1.

Figure 1

Regulation of the AM miRNome in co-ex and KO males (M) and females (F) after Filter air (FA) and Ozone (O3) exposure. Comparisons between miRNAs identified after FA or O3 exposure in co-ex females (A), males (B), and KO females (C), males (D). Significant differences observed between treatment in co-ex females, KO males and females (A,C,D; P < 0.05). (E,F) Depict the Bonferroni multiple comparisons of the miRNAs identified after FA or O3 exposure in co-ex and KO, respectively. A significant difference is observed in co-ex and KO females as a function of treatment (E,F). Significant differences (P < 0.05) in miRNA regulation were observed between sexes in co-ex (F-FA vs. M-FA, E), and in KO (F-O3 vs. M-O3, F-O3 vs. M-FA, F). ns, not significant. *p < 0.05, **p < 0.001, **p < 0.0001.