Skip to main content
. 2019 Aug 19;29(8):1036–1043. doi: 10.1089/thy.2019.0133

Table 2.

Summary of Surgical Procedures, Anaplastic Thyroid Carcinoma Viability, Resected Tumor Histopathology, and Pretreatment Mutation Profile

  Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6
Procedures TT, central ND, bilateral ND, limited resection of esophageal muscularis TT, central ND, right ND, en bloc resection of right RLN TT, central ND, left ND, en bloc resection of left RLN, shave resection of trachea TT, central ND, revision right ND, left ND, resection of dermal metastasis TT, central ND, left level IV ND, and resection of occipital scalp lesion TT, central ND
Resection of ATC Complete Complete Complete Complete Complete Complete
Residual (R) tumor classification R1 R0 R1 R0 R0 R0
Resected ATC viability, %a 50 5 <5 0 0 0
Additional component in resected tumor PTC PTC PTC PDTC, PTC PTC PTC
Pretreatment tumor mutations BRAFV600E, TP53R175H, EGFR G322S, BRAF amplificationb BRAFV600E, TP53Q331 a BRAFV600E, TP53D208V, CDKN2ApE88 a BRAFV600E BRAFV600E, ATMI1986V, MCL1 duplication BRAFV600E
a

Indicated viability of the ATC component of the postneoadjuvant treatment resected primary thyroid tumor.

b

Detected in cell-free DNA.

ATC, anaplastic thyroid carcinoma; ND, neck dissection; PDTC, poorly-differentiated thyroid carcinoma; PTC, papillary thyroid carcinoma; RLN, recurrent laryngeal nerve; TT, total thyroidectomy.