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. 2019 Aug 19;29(8):1158–1167. doi: 10.1089/thy.2019.0007

FIG. 5.

FIG. 5.

VK2809 treatment increased hepatic mitochondrial biogenesis in GSD Ia mice. Immunoblots (A) and densitometric analysis showing the protein levels of ERRα (B) and PGC1α (C). Immunoblots (D) and densitometric analysis showing the protein levels of VDAC1 (E), COXIV (F), Tom20 (G), and ATP5A (H) in the liver tissue. Bars represent the mean ± SEM. *p < 0.05, **p < 0.01. ATP5A, ATP synthase F1 subunit alpha; COXIV, cytochrome c oxidase subunit 4I1; ERRα, estrogen-related receptor alpha; PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Tom20, translocase of outer mitochondrial membrane 20; VDAC1, voltage-dependent anion channel 1.