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. 2019 Aug 16;10:1957. doi: 10.3389/fimmu.2019.01957

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Copyright © 2019 McFarlane, Mokgethi, Kaye, Hurdayal, Brombacher, Alexander and Carter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Parasite burdens in wild-type (IL-4Rα^−/lox), CD4 T cell-specific IL-4Rα deficient (Lck^creIL-4Rα^−/lox), and IL-4Rα^−/− BALB/c mice were determined at days 30 and 56 post-infection with 1–2 × 10⁷ L. donovani amastigotes in the liver (A), spleen (B), and bone marrow (C) by LDU. Representative data from one of three experiments performed (n = 5/group). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 compared to WT control (IL-4Rα^−/lox), ^#p < 0.05 Lck^creIL-4Rα^−/lox compared to IL-4Rα^−/−.