Table 1.
Strain | Mean parasite burden (+ SD) | ||
---|---|---|---|
Spleen | Liver | Bone marrow | |
IL-4Rα−/lox | 329 ± 87 | 2554 ± 334 | 645 ± 94 |
iLckcreIL-4Rα−/lox | 285 ± 47 | 1040 ± 376** | 494 ± 77 |
IL-4Rα−/− | 509 ± 87 | 2279 ± 376# | 875 ± 145 |
Mice (n = 5/treatment) were infected with L. donovani LV82 and parasite burdens were determined on day 30 post-infection.
p < 0.001 compared to WT control, **p < 0.01 compared to WT control,
p < 0.01 iLckcreIL-4Rα−/lox compared to IL-4Rα−/−.