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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: IEEE Trans Biomed Circuits Syst. 2019 May 23;13(4):608–618. doi: 10.1109/TBCAS.2019.2918761

Table III.

Benchmarking of mm-Sized. Wirelessly Powered Optogenetic Interfaces

Publication [17] [18] [19] [20] [21] This work
Technology COTS COTS COTS 0.35-μ CMOS 0.18-μ HV BCD 0.35-μ CMOS
Wireless power, operating Freq. RF, 1.5 GHz RF, 2.9 GHz RF, 13.56 MHz Photovoltaic Ultrasound, 1.314 MHz RF, 60 MHz
Number of stim. channels 1 4 1 1 4 16
Max. ILED (mA) - - 20 5 5 10
Light intensity (mW/mm2) 1-60 30 1-50 15 1.4-23 Up to 10
Stimulation Power eff.** % 19* - - 10.7* 50.3** 37.5**
efficiency * Optical eff.*** % - - 30.7*** 62.5***
Device size (mm3) 10-25 125 9.8 mm diameter, 1.3 mm thickness 1.3×1.3 ×(0.6-1.0) 2×3×6.5 2.5×2.5×1.5 (in vivo) 8×14×2 (in vivo)
Device weight 20-50 220 30 2.3 78 15 mg (in vitro) 0.5 g (in vivo)
Stim. proper Ctrl No No No No Yes Yes
In vivo experiments Yes Yes Yes No Yes Yes
*

Stim. eff. = power eff. × optical eff.

**

Power eff. = rectifier eff. × LDO eff.

***

Optical eff: output light power divided by input power.