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. 2019 Aug 19;11:7813–7824. doi: 10.2147/CMAR.S214243

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© 2019 Zhang et al.

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PKMYT1 associates with prognosis in several cancers and correlates with several crucial functional genes in ESCC. (A) Data from Kaplan–Meier Plotter showed that overexpressed of PKMYT1 related to poorer prognosis in several cancers (Copyright © 2018. Balazs Gyorffy. Data from Nagy A, Lánczky A, Menyhárt O, Győrffy B. Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets. Sci Rep. 2018;8(1):9227⁵²). (B) PKMYT1 was up-regulated in tumor tissues than normal tissues (Data from Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45(W1):W98–W102²¹). (C) PKMYT1 associated with several biomarkers which promoted tumorigenesis and metastasis in ESCC (Data from Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45(W1):W98–W102²¹). *P<0.05.

Abbreviations: PKMYT1, protein kinase, membrane associated tyrosine/threonine; ESCC, esophageal squamous cell carcinoma; OS, overall survival.