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. 2019 Aug 23;14(8):e0221413. doi: 10.1371/journal.pone.0221413

Fig 1. High VMP1 mRNA expression is correlated with shorter OS.

Fig 1

Overall survival (OS) was examined in breast cancer patients in (A) TCGA and (B) the Nordic cohort. The patients were divided into two groups according to VMP1 mRNA levels: tumors expressing high VMP1 mRNA (high ≥ mean + 1 SD) and normal VMP1 (normal < mean + 1 SD). The log rank p-values are indicated in the graphs. The number of patients at risk is shown below the graphs in tables at the indicated time points. The median OS for the TCGA cohort was 11.68 and 6.62 years for patients expressing normal and high levels of VMP1 mRNA, respectively. The hazard ratio (HR) for OS was 2.10, CI 1.09–4.04The median OS in the Nordic cohort was 16.3 and 12.6 years for patients expressing normal and high VMP1 mRNA, respectively. The HR was 1.37, CI: 0.98–1.91.