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. 2019 Aug 23;14(8):e0221413. doi: 10.1371/journal.pone.0221413

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© 2019 Amirfallah et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Distant recurrence free survival (DRFS) was analyzed in (A) cohort 1 and (B) METABRIC. The patients were divided into two groups according to VMP1 mRNA levels: tumors expressing high VMP1 mRNA (high ≥ mean + 1 SD) and normal VMP1 (normal < mean + 1 SD). The log rank p-values are indicated in the figures. The number of patients at risk is shown below the graphs at the indicated time points. The hazard ratio (HR) for DRFS in cohort 1 was 2.54, CI (1.39–4.66), and after adjusting for HER2 expression the HR was 1.95 (CI 1.04–3.68). In METABRIC the HR was 1.26 (CI 1.00–1.57) and after adjusting for HER2 expression it was HR = 1.06 (CI 0.84–1.34).