Table 3. Sex- and age-adjusted effects and corresponding 95% confidence intervals (95% CI) on body mass index (BMI) in linear regression models of the joint effects of tertiles of a BMI-associated genetic risk score (GRSBMI) and socioeconomic position indicators, calculated separately for income quartiles and education categories, with the group of having a low genetic risk score and the highest socioeconomic position as reference.
Income Quartiles | |||
n | ß (95% CI) | p | |
Lower Quartile | |||
High GRSBMI | 175 | 0.19 (-0.51; 0.89) | 0.59 |
Middle GRSBMI | 170 | -0.70 (-1.38; -0.02) | 0.05 |
Low GRSBMI | 167 | -0.65 (-1.33; 0.03) | 0.06 |
2nd Quartile | |||
High GRSBMI | 827 | 0.98 (0.33; 1.62) | <0.01 |
Middle GRSBMI | 849 | 0.31 (-0.35; 0.97) | 0.35 |
Low GRSBMI | 810 | -0.37 (-1.04; 0.29) | 0.27 |
3rd Quartile | |||
High GRSBMI | 333 | 1.24 (0.57; 1.91) | <0.01 |
Middle GRSBMI | 329 | -0.08 (-0.75; 0.58) | 0.81 |
Low GRSBMI | 343 | -0.30 (-0.96; 0.37) | 0.38 |
Highest Quartile | |||
High GRSBMI | 135 | 1.77 (1.10; 2.44) | 2.0*10−7 |
Middle GRSBMI | 172 | 0.69 (0.03; 1.34) | 0.04 |
Low GRSBMI | 172 | Ref. - | - |
Education Groups | |||
n | ß (95% CI) | p | |
≤ 10 years | |||
High GRSBMI | 295 | 4.54 (3.57; 5.51) | <2.0*10−16 |
Middle GRSBMI | 320 | 2.72 (1.74; 3.69) | 4.6*10−8 |
Low GRSBMI | 332 | 1.62 (0.64; 2.59) | <0.01 |
11–13 years | |||
High GRSBMI | 404 | 2.68 (1.93; 3.43) | 2.2*10−12 |
Middle GRSBMI | 366 | 1.80 (1.06; 2.55) | 2.2*10−6 |
Low GRSBMI | 355 | 1.18 (0.43; 1.93) | <0.01 |
14–17 years | |||
High GRSBMI | 340 | 1.99 (1.15; 2.82) | 3.2*10−6 |
Middle GRSBMI | 355 | 1.10 (0.26; 1.93) | 0.01 |
Low GRSBMI | 354 | 1.39 (0.56; 2.22) | <0.01 |
≥ 18 years | |||
High GRSBMI | 351 | 0.76 (-0.26; 1.78) | 0.14 |
Middle GRSBMI | 381 | 0.02 (-0.93; 0.98) | 0.96 |
Low GRSBMI | 361 | Ref.- | - |