Table 1. Erectile function parameters showed that si-NgBR and ICAM-1 antibody treatments decreased blood glucose and ameliorated ED.
| Groups | si-NC | si-NgBR | NgBR + anti-NC | NgBR + anti-ICAM-1 |
|---|---|---|---|---|
| Blood glucose level (mol/L) | 18.21 ± 3.42 | 11.91 ± 2.13* | 21.21±2.33 | 11.54 ± 1.26# |
| Average erectile time | 0.20 ± 0.41 | 1.85 ± 1.04* | 0.25 ± 0.44 | 1.95 ± 0.94# |
| Number of rats with erectile | 4 | 16* | 5 | 17# |
| Erectile rate (%) | 20 | 80* | 25 | 85# |
| ICP/MAP | 26.71 ± 7.56 | 42.31 ± 6.79* | 24.39 ± 6.76 | 41.75 ± 9.49# |
| Systolic percentage (%) | 23.75 ± 7.12 | 15.29 ± 6.73* | 24.13 ± 9.32 | 17.34 ± 8.56# |
| Diastolic percentage (%) | 22.13 ± 6.34 | 40.51 ± 7.21* | 21.01 ± 7.65 | 37.94 ± 7.32# |
Notes: ICP, intracavernous pressure; MAP, mean arterial pressure; blood glucose level and average erectile time were analyzed by Student t-test between groups; Number of rats with erectile and erectile rate were analyzed by chi-square test between groups
*, p < 0.05, compared with the si-NC group
#, p < 0.05, compared with the NgBR+ anti -NC group, n = 20.