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. 2019 Aug 23;14(8):e0221560. doi: 10.1371/journal.pone.0221560

Fig 8. Tulathromycin PRRSV exhibit an additive effect on the induction of apoptosis in MDMs.

Fig 8

Cell apoptotic death as detected by (A) cell death ELISA or (B, C) AnnexinV FLUOS staining in MDMs treated with HBSS (Control) or tulathromycin (1mg/mL; 1 hour; TUL), un-infected or infected with PRRSV (m.o.i = 0.5; 24 hours; virus and TUL+ Virus). Staurosporine (STS) served as a positive pro-apoptotic control. Values are expressed as (A) absorbance and (B) fluorescence ratios vs control. (A) Data represent mean ± SEM, n = 4 per group. # = P<0.05 vs control; * = P<0.05 vs tulathromycin; Δ = P<0.05 vs virus. (B) Data represent mean ± SEM, n = 5–7 per group. # = P<0.05 vs control; * = P<0.05 vs tulathromycin; Δ = P<0.05 vs virus. Pictures in panel (C) are representatives of 3 independent experiments.