Table 3.
Meta-analytical outputs for the safety of PVP compared with TURP
| Outcomes | No of studies | Sample size | Heterogeneity (total) | MD or RR (95% CI) | Test for overall effect | |||||
| PVP | TURP | χ2 | df | I2 (%) | P value | |||||
| Z | P value | |||||||||
| Operation time | 14 | 979 | 870 | 216.27 | 13 | 94 | <0.01 | 15.24 (8.91 to 21.54) | 4.72 | <0.01 |
| 6* | 429* | 428* | 6.01* | 5* | 17* | 0.31* | 10.60 (8.39 to 12.81)* | 9.40* | <0.01* | |
| Hospitalisation time | 11 | 819 | 723 | 600.62 | 10 | 98 | <0.01 | −1.98 (−2.56 to −1.39) | 6.59 | <0.01 |
| 3* | 240* | 229* | 6.29* | 2* | 68* | <0.01* | −1.83 (−2.25 to −1.40)* | 8.42* | <0.01* | |
| Catheterisation time | 14 | 861 | 794 | 964.75 | 13 | 99 | <0.01 | −1.25 (−1.58 to −0.92) | 7.48 | <0.01 |
| Blood loss | 6 | 389 | 335 | 46.05 | 5 | 89 | <0.01 | −1.33 (−2.05 to −0.61) | 3.62 | <0.01 |
| Transfusion | 14 | 1110 | 946 | 10.87 | 13 | 0 | 0.62 | 0.14 (0.08 to 0.26) | 6.10 | <0.01 |
| TUR syndrome | 7 | 590 | 435 | 0.73 | 6 | 0 | 0.99 | 0.19 (0.06 to 0.61) | 2.82 | <0.01 |
| Capsular perforation | 7 | 641 | 451 | 1.84 | 6 | 0 | 0.93 | 0.09 (0.03 to 0.26) | 4.51 | <0.01 |
| Clot retention | 8 | 699 | 504 | 1.72 | 7 | 0 | 0.97 | 0.14 (0.07 to 0.29) | 5.32 | <0.01 |
| Urinary tract infection | 13 | 1049 | 860 | 8.79 | 12 | 0 | 0.72 | 1.15 (0.85 to 1.55) | 0.89 | 0.38 |
| Acute urinary retention | 10 | 694 | 653 | 5.55 | 9 | 0 | 0.78 | 1.19 (0.80 to 1.75) | 0.86 | 0.39 |
| Urinary incontinence | 4 | 296 | 263 | 4.28 | 3 | 30 | 0.23 | 1.45 (0.74 to 2.86) | 1.08 | 0.28 |
| Bladder neck contracture | 8 | 523 | 520 | 4.32 | 7 | 0 | 0.74 | 1.05 (0.57 to 1.94) | 0.16 | 0.87 |
| Urethral stricture | 15 | 1172 | 980 | 9.37 | 14 | 0 | 0.81 | 0.81 (0.57 to 1.16) | 1.14 | 0.25 |
| Retrograde ejaculation | 4 | 320 | 314 | 15.06 | 3 | 80 | <0.01 | 0.72 (0.49 to 1.07) | 1.62 | 0.11 |
| Dysuria | 12 | 1079 | 854 | 24.80 | 11 | 58 | 0.01 | 1.76 (1.17 to 2.65) | 2.71 | <0.01 |
| Reintervention | 12 | 980 | 809 | 14.58 | 11 | 25 | 0.20 | 1.81 (1.28 to 2.56) | 3.35 | <0.01 |
*Using sensitivity analysis.
MD, mean difference; PVP, photoselective vaporisation of the prostate; RR, risk ratio; TR, syndrome=transurethral resection syndrome; TURP, transurethral resection of the prostate.