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. 2019 Aug 22;25:446–461.

Figure 3.

Figure 3

Interventional DMF treatment preserves visual acuity. A: Graph of the average number of days that mice on the interventional regimen registered an optokinetic tracking (OKT) reading deficit of 10% (left graph), 20% (center graph), or 30% (right graph) below their respective individual baseline OKT readings as a function of dimethyl fumarate (DMF; blue bar) or vehicle (red bar). B: Graph of the average lowest OKT readings for mice on the interventional treatment with DMF or vehicle. C: Graph of the average number of optic neuritis episodes for mice on the interventional regimen with DMF or vehicle. D: Graph of the average difference between the baseline and final OKT readings for mice on the interventional regimen. Statistics for all graphs determined with the Mann–Whitney U test, an asterisk denotes statistical significance, “ns” denotes not significant, and error bars represent standard error of the mean (SEM); n=8 mice for each treatment group.