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. 2019 Aug 16;10:893. doi: 10.3389/fphar.2019.00893

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Copyright © 2019 Margiotta-Casaluci, Owen, Rand-Weaver and Winter

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Overview of the effects of propranolol, losartan, and captopril on the heart rate of human, dog, rat, and zebrafish. Data are expressed as standardized mean difference (treated vs. control) ± 95% confidence interval. The data related to human, dog, and rat were retrieved from the literature, whereas the zebrafish data were generated in the present study. Each data point represents a different treatment group. The same dataset was used to perform a quantitative meta-analysis. A detailed description of the results is provided in the Supplementary Material Data Sheet 1 .