Table 1.
Factors | Index Colonoscopy Findings | ||||
---|---|---|---|---|---|
Group 1 1–2 diminutive* adenomas | Group 2 1–2 adenomas < 1 cm, one or more small** | Group 3 3–10 diminutive* adenomas | Group 4 3–10 adenomas < 1 cm, one or more small** | Group 5 Advanced adenoma*** | |
N | 2568 | 1294 | 293 | 425 | 1503 |
Age (mean + S.D.) | 59.1 ± 8.9 | 58.7 ± 9.5 | 62.5 ± 8.9 | 62.5 ± 9.1 | 60.0 ± 9.7 |
Sex (% male) | 1387 (54.0%) |
744 (57.5%) |
204 (69.6%) |
309 (72.7%) |
890 (59.2%) |
BMI | 28.5 ± 5.9 | 28.6 ± 6.1 | 29.7 ± 6.7 | 29.9 ± 5.8 | 29.2 ± 6.1 |
Family history of CRC (first degree relative) | 617 (24.0%) |
305 (23.6%) |
68 (23.2%) |
92 (21.6%) |
313 (20.8%) |
Current smokers | 239 (9.9%) |
135 (10.17%) | 39 (13.5%) |
46 (11.2%) |
211 (14.5%) |
Aspirin use (regular) | 995 (38.7%) |
536 (41.4%) |
115 (39.2%) |
217 (51.1%) |
556 (37.0%) |
Alcohol (at least 5 drinks per week) | 804 (31.3%) |
384 (29.7%) |
104 (35.5%) |
129 (30.4%) |
448 (29.8%) |
Education (HS or more) | 2383 (92.8%) |
1207 (93.3%) |
272 (92.8%) |
389 (91.5%) |
1379 (91.7%) |
Regular exercise (at least 1/week) | 1444 (56.2%) |
699 (54.0%) |
145 (49.5%) |
217 (51.1%) |
742 (49.4%) |
Previous adenomas | 795 (31.5) |
388 (30.6%) |
135 (48.0%) |
197 (47.7%) |
397 (27.0%) |
Clinically significant serrated polyps**** at index exam | 190 (7.5%) |
138 (10.8%) |
22 (7.6%) |
42 (9.9%) |
149 (11.3%) |
Months to surveillance exam | 57.9 ± 19.2 | 56.7 ± 12.1 | 42.5 ± 15.1 | 40.6 ± 16.0 | 38.6 ± 23.0 |
Diminutive = <5 mm;
Small = 5–9 mm;
Advanced adenomas: adenomas ≥1cm or those with villous elements, high-grade dysplasia, or CRC.
Clinically Significant serrated polyps: all SSA/Ps, TSAs, HPs >1 cm anywhere in the colon or any HP > 5mm in the proximal colon